Causes of Mast Cell Tumors in Dogs. Like other types of cancer in dogs, mast cell tumors are likely caused by a mix of genetic and environmental factors. There is a receptor on the surface of mast cells called c-kit. Current research suggests that mast cell tumors are the result of a mutation in this c-kit receptor.. Mast cell tumors are a common cancer in dogs and cats. Most are located on the skin or in the tissue layer below the skin, called the subcutaneous tissue. Mast cell tumors are considered a Great Mimicker and can have a wide range of appearances. Any lump or bump you find on your dog that persists for over a week should be examined by a vet.
My dog had a small grade 1 mast cell tumor removed about 4 months ago. It was on her shoulder
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Mast cell tumor, dog. Photograph of a Boston Terrier with a mast cell tumor infiltrating the left inguinal lymph node. Notice the bruising and ecchymosis. The original tumor appeared as a fleshy skin tag on the left caudal thigh for 3 years before it metastasized. Courtesy of Dr. Alice Villalobos. In these topics.. Treating mast cell tumors in dogs. When it comes to treating a mast cell tumor, your dog’s veterinary oncologist will evaluate a variety of factors before making treatment recommendations. They will then be able to inform you of the overall prognosis and best treatment options. Surgery — A surgical removal is a good option for a mast cell.