What are the side effects of OPTIFAST®? You MAY have irritability, headache, bad breath, fatigue, constipation. Usually patients have side effects only during first 1-2 weeks of the program.. Upset stomach or throwing up. Diarrhea. Constipation. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088.
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